Steady-State Free Precession sequences for high and low field NMR spectroscopy in solution: Challenges and opportunities.

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Author(s): MORAES, T. B.; KOCK, F. V. C.; SALOME, K. S.; BARISON, A.; SIMPSON, A.; COLNAGO, L. A.

Summary: The receptivity of NMR spectroscopy is low when compared to other techniques. Historically, increasing the strength of the static magnetic field has been the major approach to increase NMR sensitivity. In recent years several polarization transfer protocols have been used to enhance the signal-to-noise ratio (SNR), although they require special accessories and/or sample preparation. In this paper, we consider both the challenges and opportunities of steady-state free precession (SSFP) pulse sequences as a simple and efficient alternative to enhance SNR, in standard high-resolution and benchtop low-resolution NMR spectrometers. The maximum gain in these sequences is obtained with the shortest time between the pulses (Tp). However, when Tp

Publication year: 2023

Types of publication: Journal article

Observation

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